"Purines: The Powerhouses Behind DNA, RNA, and Energy"
International Chemistry Scientist Awards
Purines are nitrogen-containing heterocyclic compounds that play a vital role in biological systems. They are key components of nucleotides, the building blocks of DNA and RNA, with adenine (A) and guanine (G) being the two primary purine bases. Beyond genetics, purines are involved in energy metabolism through molecules like ATP and GTP, act as signaling molecules (e.g., cyclic AMP), and contribute to enzyme co-factors such as NADH and coenzyme A. Purine metabolism is tightly regulated in the body, and its imbalance can lead to disorders like gout or kidney stones. The study of purines extends into biochemistry, medicine, pharmacology, and molecular biology, offering insight into cellular processes, disease mechanisms, and drug development.
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