Dienylation in Organic Synthesis #worldresearchawards #researchaward #researcher #dienylation
Dienylation is a powerful and versatile strategy in organic chemistry that enables the construction of conjugated diene systems key structural motifs found in natural products, pharmaceuticals, polymers, and functional materials. This video dives into the fundamentals and recent advances of dienylation reactions, revealing how they unlock efficient pathways for carbon–carbon bond formation and molecular complexity. At its core, dienylation involves the introduction of a dienyl group into a molecular framework, often through transition-metal catalysis or selective coupling reactions. These processes allow chemists to precisely control regioselectivity and stereochemistry, which are critical for tailoring chemical reactivity and biological activity. Palladium, nickel, copper, and emerging earth-abundant metal catalysts play essential roles in enabling mild, efficient, and sustainable dienylation protocols. Conjugated dienes produced through dienylation are highly reactive intermediates...